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HOUSTON -- The Astros had established such a comfort in the reliability of their high-leverage relievers that little could prepare them for what unfolded on Friday night against the Angels.Right-handers Luke Gregerson and Ken Giles, half of the Astros quartet of rock-solid relief pitchers (a group that also includes right-handers Chris Devenski and Will Harris) combined to cough up a three-run lead in a 10-6 loss that severely damaged the Astros playoff aspirations. Gregerson allowed a run on two hits in the eighth inning; Giles blew his fifth save by coming apart at the seams in the ninth.Giles surrendered six earned runs on three hits and three walks, inflating his ERA from 3.47 to 4.31 in the process. With eight games remaining in their season and their deficit for the second American League wild card now 21/2 games behind the Tigers, the Astros were left floored by the development involving Giles in particular.Toughest inning of the year, Astros manager A.J. Hinch said. For a lot of reasons.Added Giles: I didnt do my job. Didnt make my pitches. Thats all I can say. I just didnt do it.The Astros (81-73) have lost twice as many games to the Angels (68-86) over the first two games of this series than they did in the first 12 meetings between the teams this season. At best, they can salvage a split of the four-game set with victories on Saturday night and Sunday.Right-hander Brad Peacock (0-0, 2.86 ERA) will make his fourth start for the Astros in the third game of the series. Peacock, who has filled in admirably for injured left-hander Dallas Keuchel (left shoulder inflammation), is 3-0 with a 4.50 ERA in five career games (three starts) against the Angels. He has not pitched against Los Angeles this season.Angels right-hander Jhoulys Chacin (4-6, 5.26 ERA) will make his 33rd appearance and 21st start of the season. Chacin is 1-2 with a 4.50 ERA in five career games (four starts) against the Astros, including 0-1 with a 9.00 ERA in two games this season.Chacin, who will make his 16th start for the Angels, has toggled between the rotation and bullpen for the Angels, rejoining the rotation on Sept. 14 against the Mariners after making four appearances out of the bullpen between Aug. 27 and Sept. 10. In his last four starts for the Angels, Chacin has pitched to a 0.87 ERA.I think Jhoulys has the ability to do both, Angels manager Mike Scioscia said. Hes done very well out of our pen and recently with some adjustments that hes made hes been very effective as a starter. I think his upside is still as a major league starter and I know thats what he wants to do and I think he can be effective doing that but if not hes shown he can throw out of our bullpen. Puma Authentic Nz . -- Bobby Ryan helped the U. Wholesale Puma Shoes . -- Damian Lillard and LaMarcus Alrdridge were again the go-to duo for the Trail Blazers against the Kings. http://www.wholesalepumanz.com/ . Rob Manfred, baseballs chief operating officer, testified last week during the grievance filed by the players union to overturn Rodriguezs 211-game suspension. A person familiar with the hearing, speaking on condition of anonymity, told The Associated Press on Saturday that Manfred testified the sport wasnt concerned whether Bosch distributed performance-enhancing drugs to minors because MLBs interest was his relationship with players under investigation. Cheap Puma For Sale Nz .ca NFL Power Rankings, overtaking the Denver Broncos and remaining ahead of NFC competition San Francisco, Carolina and New Orleans. Puma Shoes Nz Cheap . The Islanders dealt Thomas Vanek to the Montreal Canadiens after less than a year on Long Island. Meanwhile, the Oilers dealt long-time sniper Ales hemsky to the Ottawa Senators on Wednesday for a fifth-round pick in 2014 and a third-rounder in 2015. ABU DHABI, United Arab Emirates -- Jenson Buttons Formula One farewell ended in sad style when he retired early in the season-ending Abu Dhabi Grand Prix on Sunday because of a suspension problem.Button has an option to drive for the McLaren team in 2018, but he said before this race that he does not expect to come back.My race was short, but I loved everything else. I was really emotional before I got in the car, Button said. It was such a special atmosphere to have the whole team and all my friends and family cheering me on my way into the garage. Im just glad I was wearing my sunglasses at that moment.He was on lap 13 when some sparks flew off his car and he went straight on and cut over some grass before getting back on track. The British driver appeared to be struggling with a suspension or a steering issue.I dont think weve ever had a failure like this, a despondent Button said as his car limped back into the garage. Im just glad I was able to figure it out before I hit the brakes. Its always been a massive strength of our team that components so rarely fail, but today of all days something did.Button, a hugely popular figure among fans and other drivers alike, stepped out and waved to the crowd one last time befoore being comforted by mechanics and his mother.ddddddddddddIm very content with all Ive achieved in my career, Button said. Now, its done.Button is making way for Belgian driver Stoffel Vandoorne, who will partner two-time F1 champion Fernando Alonso at McLaren next year while Button works in an advisory role within the team.Its a shame that Jensons final race came to an early end, but hell still be around next year, said Alonso, who finished the race in 10th place. Hell be a huge asset for us in his new role.The 36-year-old Button won the F1 title against the odds in 2009 for the Brawn team, and has 15 GP victories overall.After competing in his first F1 race at age 20, this race was his 305th GP start, putting him just one behind seven-time F1 champion Michael Schumacher of Germany.Im holding it together, an emotional Button said before the race when the drivers were paraded around the track.Unfortunately, he did not get the farewell he craved and a mechanical failure denied him one last checkered flag.I live in the moment, though, Button said. Tonights going to be a hell of a lot of fun. ' ' '